BDBM781898 (S)-2-amino-N-(1-(5-((1-cyclopropyl-1H-pyrazol-4-yl)ethynyl)-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::US12447151, Example 2
SMILES C[C@H](NC(=O)c1c(N)nn2cccnc12)c1nc2cccc(C#Cc3cnn(C4CC4)c3)c2c(=O)n1-c1ccccc1
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 781898
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Human)
HIS Pharmaceutical Co.
US Patent
HIS Pharmaceutical Co.
US Patent
Affinity DataIC50: 0.580nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then the b...More data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
HIS Pharmaceutical Co.
US Patent
HIS Pharmaceutical Co.
US Patent
Affinity DataIC50: 191nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then the b...More data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
HIS Pharmaceutical Co.
US Patent
HIS Pharmaceutical Co.
US Patent
Affinity DataIC50: 214nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then the b...More data for this Ligand-Target Pair
Ligand Info
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
HIS Pharmaceutical Co.
US Patent
HIS Pharmaceutical Co.
US Patent
Affinity DataIC50: 466nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then the b...More data for this Ligand-Target Pair
Ligand Info