BDBM781919 US20250320234, Compound 25

SMILES COC[C@@H](NC(=O)c1cnccn1)C(=O)N[C@@H](CCOc1ccc(Cl)c(F)c1)B(O)O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 781919   

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM781919(US20250320234, Compound 25)
Affinity DataIC50: 50nMAssay Description:In this Example, LONP1 (NM_004793.4) activity was measured by a FRET-based assay for protease activity using a fluorogenic peptide DabcylYRGIT(2Abu)S...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent