BDBM782981 N-methyl-2-(methyl(2-oxo-4-(o-tolyl)-2H-chromen-7-yl)amino)acetamide::US20250326732, Example 177

SMILES CNC(=O)CN(C)c1ccc2c(-c3ccccc3C)cc(=O)oc2c1

InChI Key

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782981   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM782981(N-methyl-2-(methyl(2-oxo-4-(o-tolyl)-2H-chromen-7-...)
Affinity DataIC50: 50nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent