BDBM783059 N-(1-(N,N-Dimethylsulfamoyl)piperidin-4-yl)-6-(1H-imidazol-1-yl)-4-methylpicolinamide::US20250326739, Compound 18A

SMILES Cc1cc(C(=O)NC2CCN(S(=O)(=O)N(C)C)CC2)nc(-n2ccnc2)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783059   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM783059(N-(1-(N,N-Dimethylsulfamoyl)piperidin-4-yl)-6-(1H-...)
Affinity DataIC50: 5.5nMAssay Description:Required reaction buffer, required CD38 concentration in reaction buffer and required e-NAD concentration in reaction buffer were prepared. Thereafte...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM783059(N-(1-(N,N-Dimethylsulfamoyl)piperidin-4-yl)-6-(1H-...)
Affinity DataIC50: 30nMAssay Description:Required reaction buffer, required CD38 concentration in reaction buffer and required e-NAD concentration in reaction buffer were prepared. Thereafte...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent