BDBM783240 2,2''-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-(6-(4- fluorobenzyl)-3,3- dimethyl-5-oxo- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)piperidin-3- yl)acetamide)::US20250326771, Compound 48

SMILES Cc1ccc(Cc2cc3c([nH]c2=O)C(C)(C)CN3C(=O)CN2C[C@@H](C)NC[C@@H]2CN2CCC[C@@H](NC(=O)Cc3ccc(CC(=O)N[C@@H]4CCCN(C[C@H]5CN[C@H](C)CN5CC(=O)N5CC(C)(C)c6[nH]c(=O)c(Cc7ccc(F)cc7)cc65)C4)cc3)C2)cc1

InChI Key InChIKey=YYRUJTJQHANLFF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 783240   

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783240BDBM783240(2,2'-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783240BDBM783240(2,2'-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783240BDBM783240(2,2'-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783240BDBM783240(2,2'-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-...)
Affinity DataIC50: 3.06E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783240BDBM783240(2,2'-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-...)
Affinity DataIC50: 3.06E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783240BDBM783240(2,2'-(1,4- phenylene)bis(N-((R)- 1-(((2R,5R)-1-(2-...)
Affinity DataIC50: 3.06E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent