BDBM783307 1,1''-(2,2''- ((3R,3''R,6R,6''R)- (((2S,2''S)- (((methylenebis(4,1- phenylene))bis(oxy)) bis(methylene))bis (morpholine- 2,4- diyl))bis(methylene)) bis(3-methylpiperazine- 6,1- diyl))bis(acetyl))bis(6- (4-fluorobenzyl)-3,3,4- trimethyl-1,2,3,4- tetrahydro-5H- pyrrolo[3,2-b]pyridin- 5-one)::US20250326771, Compound 115

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3c2cc(Cc2ccc(F)cc2)c(=O)n3C)[C@@H](CN2CCO[C@H](COc3ccc(Cc4ccc(OC[C@@H]5CN(C[C@H]6CN[C@H](C)CN6CC(=O)N6CC(C)(C)c7c6cc(Cc6ccc(F)cc6)c(=O)n7C)CCO5)cc4)cc3)C2)CN1

InChI Key InChIKey=RNQGJHLFXJEHDB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 783307   

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783307BDBM783307(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((methy...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783307BDBM783307(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((methy...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783307BDBM783307(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((methy...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783307BDBM783307(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((methy...)
Affinity DataIC50: 6.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783307BDBM783307(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((methy...)
Affinity DataIC50: 6.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783307BDBM783307(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)- (((methy...)
Affinity DataIC50: 3.06E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent