BDBM783372 (2S,2''S)-N,N''-(1,4- phenylenebis(methylene)) bis(4-(((2R,5R)-1- (2-(3,3-dimethyl-5- oxo-6-(2,4,6- trichlorobenzyl)- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)morpholine- 2-carboxamide)::US20250326771, Compound 180

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3[nH]c(=O)c(Cc4c(Cl)cc(Cl)cc4Cl)cc32)[C@@H](CN2CCO[C@H](C(=O)NCc3ccc(CNC(=O)[C@@H]4CN(C[C@H]5CN[C@H](C)CN5CC(=O)N5CC(C)(C)c6[nH]c(=O)c(Cc7c(Cl)cc(Cl)cc7Cl)cc65)CCO4)cc3)C2)CN1

InChI Key InChIKey=JZTBWEAWVJJSPC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 783372   

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783372BDBM783372((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783372BDBM783372((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783372BDBM783372((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783372BDBM783372((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 3.06E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783372BDBM783372((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 3.06E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent