BDBM783605 Isopropyl 2-((2R,5S)-4-(6-cyano-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridin-4-yl)-2,5-dimethylpiperazin-1-yl)-2-(4-fluorophenyl)acetate::US12454531, Example 2

SMILES N#Cc1ccc2c(n1)c(N1C[C@@H](C)N(C(C(=O)OC(C)C)c3ccc(F)cc3)C[C@@H]1C)cc(=O)n2C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783605   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM783605(Isopropyl 2-((2R,5S)-4-(6-cyano-1-methyl-2-oxo-1,2...)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/17/2026
Entry Details US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM783605(Isopropyl 2-((2R,5S)-4-(6-cyano-1-methyl-2-oxo-1,2...)
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/17/2026
Entry Details US Patent