BDBM783608 2-((2R,5S)-4-(6-cyano-1-methyl-2-oxo-1,2-dihydro-1,5-naphthyridin-4-yl)-2,5-dimethylpiperazin-1-yl)-N-(2,2-difluoroethyl)-2-(4-fluorophenyl)acetamide::US12454531, Example 5

SMILES N#Cc1ccc2c(n1)c(N1C[C@@H](C)N(C(C(=O)NCC(F)F)c3ccc(F)cc3)C[C@@H]1C)cc(=O)n2C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783608   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM783608(2-((2R,5S)-4-(6-cyano-1-methyl-2-oxo-1,2-dihydro-1...)
Affinity DataIC50: 2.04E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/17/2026
Entry Details US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM783608(2-((2R,5S)-4-(6-cyano-1-methyl-2-oxo-1,2-dihydro-1...)
Affinity DataIC50: 3.27E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/17/2026
Entry Details US Patent