BDBM783653 4-((2S,5R)-2,5-diethyl-4-(2-morpholino-2-oxo-1-(4-(trifluoromethyl)phenyl)ethyl)piperazin-1-yl)-1-methyl-2-oxo-1,2-dihydropyrido[3,2-d]pyrimidine-6-carbonitrile::US12454531, Example 53

SMILES CC[C@H]1CN(C(C(=O)N2CCOCC2)c2ccc(C(F)(F)F)cc2)[C@H](CC)CN1c1nc(=O)n(C)c2ccc(C#N)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783653   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM783653(4-((2S,5R)-2,5-diethyl-4-(2-morpholino-2-oxo-1-(4-...)
Affinity DataIC50: 1.97E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/17/2026
Entry Details US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM783653(4-((2S,5R)-2,5-diethyl-4-(2-morpholino-2-oxo-1-(4-...)
Affinity DataIC50: 3.29E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/17/2026
Entry Details US Patent