BDBM783820 7-fluoro-3-(3-(4-(4- fluorophenyl)piperazin-1- yl)propyl)isoquinolin-1(2H)- one::US12459899, Example 15

SMILES O=c1[nH]c(CCCN2CCN(c3ccc(F)cc3)CC2)cc2ccc(F)cc12

InChI Key InChIKey=YSHSZRTYEXCERR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783820   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783820BDBM783820(7-fluoro-3-(3-(4-(4- fluorophenyl)piperazin-1- yl)...)
Affinity DataIC50: 4.01nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent