BDBM783830 7-fluoro-3-(3-(4-(4- fluorophenyl)-3,6- dihydropyridin-1(2H)- yl)propyl)isoquinolin-1(2H)- one::US12459899, Example 48

SMILES O=c1[nH]c(CCCN2CC=C(c3ccc(F)cc3)CC2)cc2ccc(F)cc12

InChI Key InChIKey=ZVPDWPLKYKKUOF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783830   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783830BDBM783830(7-fluoro-3-(3-(4-(4- fluorophenyl)-3,6- dihydropyr...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783830BDBM783830(7-fluoro-3-(3-(4-(4- fluorophenyl)-3,6- dihydropyr...)
Affinity DataIC50: 1.32nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent