BDBM783866 US20250340516, Example 12::methyl 2-(1-((R)-2-((1-oxo-4-(o-tolyl)-1,2-dihydroisoquinolin-7-yl)oxy)propanoyl)piperidin-3-yl)acetate

SMILES Cc1ccccc1c3c[nH]c(=O)c4cc(O[C@H](C)C(=O)N2CCC[C@@H](CC(=O)O)C2)ccc34

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783866   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM783866(methyl 2-(1-((R)-2-((1-oxo-4-(o-tolyl)-1,2-dihydro...)
Affinity DataIC50: 60nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent