BDBM783874 2-((Trans-4-(2-((R)-4-(benzo[b]thiophen-4-yl)-2-methylpiperazin-1-yl)ethyl)cyclohexyl)amino)pyrimidine-5-carbonitrile::US12459931, Example 44

SMILES N#Cc1cnc(N[C@H]2CC[C@H](CCN3CCN(c4cccc5sccc45)C[C@H]3C)CC2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783874   

TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandPNGBDBM783874(2-((Trans-4-(2-((R)-4-(benzo[b]thiophen-4-yl)-2-me...)
Affinity DataIC50: 1.58nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandPNGBDBM783874(2-((Trans-4-(2-((R)-4-(benzo[b]thiophen-4-yl)-2-me...)
Affinity DataIC50: 2.59nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent