BDBM783879 N-(Trans-4-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)ethyl)cyclohexyl)-5-fluoropyrimidin-2-amine::US12459931, Example 49

SMILES Fc1cnc(N[C@H]2CC[C@H](CCN3CCN(c4cccc5sccc45)CC3)CC2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783879   

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandPNGBDBM783879(N-(Trans-4-(2-(4-(benzo[b]thiophen-4-yl)piperazin-...)
Affinity DataIC50: 0.340nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetD(3) dopamine receptor(Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandPNGBDBM783879(N-(Trans-4-(2-(4-(benzo[b]thiophen-4-yl)piperazin-...)
Affinity DataIC50: 2.43nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent