BDBM783925 7-fluoro-3-(3-(4-(3- nitrophenyl)piperazin-1- yl)propyl)isoquinolin-1(2H)- one::US12459899, Example 11

SMILES O=c1[nH]c(CCCN2CCN(c3cccc([N+](=O)[O-])c3)CC2)cc2ccc(F)cc12

InChI Key InChIKey=AWVCXQOOLRGMML-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783925   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783925BDBM783925(7-fluoro-3-(3-(4-(3- nitrophenyl)piperazin-1- yl)p...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent