BDBM783937 3-fluoro-4-(4-(3-(8-fluoro-5- methyl-1-oxo-1,2- dihydroisoquinolin-3- yl)propyl)piperazin-1- yl)benzonitrile::US12459899, Example 26

SMILES Cc1ccc(F)c2c(=O)[nH]c(CCCN3CCN(c4ccc(C#N)cc4F)CC3)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783937   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandPNGBDBM783937(3-fluoro-4-(4-(3-(8-fluoro-5- methyl-1-oxo-1,2- di...)
Affinity DataIC50: 0.650nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent