BDBM783951 7-fluoro-3-(3-(4-(4- fluorophenyl)piperazin-1- yl)propyl)-5-methyl- isoquinolin-1(2H)-one::US12459899, Example 40

SMILES Cc1cc(F)cc2c(=O)[nH]c(CCCN3CCN(c4ccc(F)cc4)CC3)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783951   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandPNGBDBM783951(7-fluoro-3-(3-(4-(4- fluorophenyl)piperazin-1- yl)...)
Affinity DataIC50: 0.650nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent