BDBM783953 8-fluoro-3-(3-(4-(4- fluorophenyl)-3,6- dihydropyridin-1(2H)- yl)propyl)isoquinolin-1(2H)- one::US12459899, Example 42

SMILES O=c1[nH]c(CCCN2CC=C(c3ccc(F)cc3)CC2)cc2cccc(F)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783953   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandPNGBDBM783953(8-fluoro-3-(3-(4-(4- fluorophenyl)-3,6- dihydropyr...)
Affinity DataIC50: 0.650nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent