BDBM784004 1''-(3-(7-fluoro-1-oxo-1,2- dihydroisoquinolin-3- yl)propanoyl)-1'',2'',3'',6''- tetrahydro-[2,4''-bipyridine]-5- carbonitrile::US12459899, Example 96

SMILES N#Cc1ccc(C2=CCN(C(=O)CCc3cc4ccc(F)cc4c(=O)[nH]3)CC2)nc1

InChI Key InChIKey=UHDQTLFCIHHQNN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784004   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784004BDBM784004(1'-(3-(7-fluoro-1-oxo-1,2- dihydroisoquinolin-3- y...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent