BDBM784021 3-(3-(4-(2,4-difluorophenyl)- 3,6-dihydropyridin-1(2H)-yl)-3- oxopropyl)-7-fluoroisoquinolin- 1(2H)-one::US12459899, Example 113

SMILES O=C(CCc1cc2ccc(F)cc2c(=O)[nH]1)N1CC=C(c2ccc(F)cc2F)CC1

InChI Key InChIKey=YSMXPVOAIHJOCV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784021   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784021BDBM784021(3-(3-(4-(2,4-difluorophenyl)- 3,6-dihydropyridin-1...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent