BDBM784054 methyl 4-(4-(3-(8-fluoro-5- methyl-1-oxo-1,2- dihydroisoquinolin-3- yl)propanoyl)piperazin-1- yl)benzoate::US12459899, Example 146

SMILES COC(=O)c1ccc(N2CCN(C(=O)CCc3cc4c(C)ccc(F)c4c(=O)[nH]3)CC2)cc1

InChI Key InChIKey=FODCTULYAWPZRP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784054   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784054BDBM784054(methyl 4-(4-(3-(8-fluoro-5- methyl-1-oxo-1,2- dihy...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent