BDBM784067 5-fluoro-2-(4-(3-(7-fluoro-5- methyl-1-oxo-1,2- dihydroisoquinolin-3- yl)propanoyl)piperazin-1- yl)benzonitrile::US12459899, Example 159

SMILES Cc1cc(F)cc2c(=O)[nH]c(CCC(=O)N3CCN(c4ccc(F)cc4C#N)CC3)cc12

InChI Key InChIKey=DFHTVRBZOCZPEC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784067   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784067BDBM784067(5-fluoro-2-(4-(3-(7-fluoro-5- methyl-1-oxo-1,2- di...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent