BDBM784093 8-fluoro-3-(3-(4- isobutyrylpiperazin-1-yl)-3- oxopropyl)isoquinolin-1(2H)- one::US12459899, Example 186

SMILES CC(C)C(=O)N1CCN(C(=O)CCc2cc3cccc(F)c3c(=O)[nH]2)CC1

InChI Key InChIKey=AOXBKGRKRQLVQX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784093   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784093BDBM784093(8-fluoro-3-(3-(4- isobutyrylpiperazin-1-yl)-3- oxo...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent