BDBM784112 6-(8-(3-(7-fluoro-5-methyl-1- oxo-1,2-dihydroisoquinolin-3- yl)propyl)-3,8- diazabicyclo[3.2.1]octan-3- yl)nicotinonitrile::US12459899, Example 205

SMILES Cc1cc(F)cc2c(=O)[nH]c(CCCN3C4CCC3CN(c3ccc(C#N)cn3)C4)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784112   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandPNGBDBM784112(6-(8-(3-(7-fluoro-5-methyl-1- oxo-1,2-dihydroisoqu...)
Affinity DataIC50: 0.650nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent