BDBM784128 4-(4-(3-(5-oxo-5,6-dihydro-1,6- naphthyridin-7- yl)propyl)piperazin-1- yl)benzonitrile::US12459899, Example 221

SMILES N#Cc1ccc(N2CCN(CCCc3cc4ncccc4c(=O)[nH]3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784128   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandPNGBDBM784128(4-(4-(3-(5-oxo-5,6-dihydro-1,6- naphthyridin-7- yl...)
Affinity DataIC50: 0.650nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent