BDBM784130 7-(3-(4-(4- fluorophenyl)piperazin-1- yl)propyl)-1,6-naphthyridin- 5(6H)-one::US12459899, Example 223

SMILES O=c1[nH]c(CCCN2CCN(c3ccc(F)cc3)CC2)cc2ncccc12

InChI Key InChIKey=AJKZXDMIIUMOAJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784130   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784130BDBM784130(7-(3-(4-(4- fluorophenyl)piperazin-1- yl)propyl)-1...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent