BDBM784138 7-(3-(3-(5-fluoropyridin-2-yl)- 3,8-diazabicyclo[3.2.1]octan- 8-yl)propyl)-1,6-naphthyridin- 5(6H)-one::US12459899, Example 231

SMILES O=c1[nH]c(CCCN2C3CCC2CN(c2ccc(F)cn2)C3)cc2ncccc12

InChI Key InChIKey=GSRUKEVQZHYNCG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784138   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784138BDBM784138(7-(3-(3-(5-fluoropyridin-2-yl)- 3,8-diazabicyclo[3...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent