BDBM784153 4-(8-(3-(5-oxo-5,6-dihydro-1,6- naphthyridin-7-yl)propanoyl)- 3,8-diazabicyclo[3.2.1]octan- 3-yl)benzonitrile::US12459899, Example 246

SMILES N#Cc1ccc(N2CC3CCC(C2)N3C(=O)CCc2cc3ncccc3c(=O)[nH]2)cc1

InChI Key InChIKey=OKXJEKNDLPKVTP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784153   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784153BDBM784153(4-(8-(3-(5-oxo-5,6-dihydro-1,6- naphthyridin-7-yl)...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent