BDBM784210 1-((R)-2-((1-oxo-4-(o-tolyl)-1,2-dihydroisoquinolin-7-yl)oxy)propanoyl)-3-propylpiperidine-3-carboxylic acid::US20250340516, Example 67

SMILES CCC[C@]1(C(=O)O)CCCN(C(=O)[C@@H](C)Oc2ccc3c(-c4ccccc4C)c[nH]c(=O)c3c2)C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784210   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM784210(1-((R)-2-((1-oxo-4-(o-tolyl)-1,2-dihydroisoquinoli...)
Affinity DataIC50: 40nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent