BDBM784257 US20250340529, Compound 472

SMILES O=C1COc2cc(-c3cccc(-c4cccc(-c5ccc6c(c5)OCC(=O)N6C[C@@H]5C[C@@H](O)CN5)c4Cl)c3Cl)ccc2N1C[C@@H]1C[C@@H](O)CN1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784257   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Ascletis Bioscience Co.

US Patent
LigandPNGBDBM784257(US20250340529, Compound 472)
Affinity DataIC50: 5.27nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent