BDBM784273 US20250340529, Compound 554

SMILES O=C(O)[C@H](CO)NCCN1C(=O)COc2cc(-c3cccc(-c4cccc(-c5cc6c(cc5F)N(CCN[C@@H](CO)C(=O)O)C(=O)CO6)c4Cl)c3Cl)c(F)cc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784273   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Ascletis Bioscience Co.

US Patent
LigandPNGBDBM784273(US20250340529, Compound 554)
Affinity DataIC50: 5.51nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent