BDBM784274 US20250340529, Compound 388

SMILES O=C1CC[C@@H](CN2C(=O)COc3cc(-c4cccc(-c5cccc(-c6cc7c(cc6F)N(C[C@@H]6CCC(=O)N6)C(=O)CO7)c5Cl)c4Cl)c(F)cc32)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784274   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Ascletis Bioscience Co.

US Patent
LigandPNGBDBM784274(US20250340529, Compound 388)
Affinity DataIC50: 1.10nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent