BDBM784278 US20250340529, Compound 482

SMILES O=C(O)[C@@H]1C[C@@H](O)CN1CCN1C(=O)COc2cc(-c3cccc(-c4cccc(-c5ccc6c(c5)OCC(=O)N6CCN5C[C@@H](O)C[C@H]5C(=O)O)c4Cl)c3Cl)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784278   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Ascletis Bioscience Co.

US Patent
LigandPNGBDBM784278(US20250340529, Compound 482)
Affinity DataIC50: 6.72nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent