BDBM784465 2-(2-Amino-5-(2-((4-(4- (dimethylcarbamoyl)phenyl)piperidin- 1-yl)methyl)-1-methyl-1H-pyrrolo[2,3- b]pyridin-4-yl)phenyl)-2-oxoacetic acid::US20250340551, Example 1j13

SMILES [H]C(=O)c1cc(-c2ccnc3c2cc(CN2CCC(c4ccc(C(=O)N(C)C)cc4)CC2)n3C)ccc1N

InChI Key

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784465   

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784465(2-(2-Amino-5-(2-((4-(4- (dimethylcarbamoyl)phenyl)...)
Affinity DataKd:  12.8nMAssay Description:SPR was used to confirm and quantify binding of compounds to human STAT6. Biacore instruments from the 8K-series (Cytiva) were used, and measurements...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent