BDBM784725 N-(2,6-dimethylphenyl)-2- ((6-(4-(2- hydroxyethyl)piperazin-1-yl)- 2-methylpyrimidin-4- yl)amino)thiazole-5- carboxamide::US20250340886, Compound A12

SMILES Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3C)s2)cc(N2CCN(CCO)CC2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 784725   

TargetSerine/threonine-protein kinase SIK3(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784725(N-(2,6-dimethylphenyl)-2- ((6-(4-(2- hydroxyethyl)...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784725(N-(2,6-dimethylphenyl)-2- ((6-(4-(2- hydroxyethyl)...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784725(N-(2,6-dimethylphenyl)-2- ((6-(4-(2- hydroxyethyl)...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent