BDBM784731 N-(2-chloro-6-methylphenyl)-2- ((2-methyl-6-(4- methylpiperazin-1-yl)pyrimidin- 4-yl)amino)thiazole-5- carboxamide::US20250340886, Compound B5

SMILES Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(C)CC2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 784731   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784731(N-(2-chloro-6-methylphenyl)-2- ((2-methyl-6-(4- me...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetTyrosine-protein kinase ABL1(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784731(N-(2-chloro-6-methylphenyl)-2- ((2-methyl-6-(4- me...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784731(N-(2-chloro-6-methylphenyl)-2- ((2-methyl-6-(4- me...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784731(N-(2-chloro-6-methylphenyl)-2- ((2-methyl-6-(4- me...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784731(N-(2-chloro-6-methylphenyl)-2- ((2-methyl-6-(4- me...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent