BDBM784734 N-(2-chloro-6-ethoxyphenyl)-2- ((6-(4-(2- hydroxyethyl)piperazin-1-yl)- 2-methylpyrimidin-4- yl)amino)thiazole-5- carboxamide::US20250340886, Compound B8

SMILES CCOc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(N3CCN(CCO)CC3)nc(C)n2)s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 784734   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784734(N-(2-chloro-6-ethoxyphenyl)-2- ((6-(4-(2- hydroxye...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetTyrosine-protein kinase ABL1(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784734(N-(2-chloro-6-ethoxyphenyl)-2- ((6-(4-(2- hydroxye...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784734(N-(2-chloro-6-ethoxyphenyl)-2- ((6-(4-(2- hydroxye...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
iOmx Therapeutics

US Patent
LigandPNGBDBM784734(N-(2-chloro-6-ethoxyphenyl)-2- ((6-(4-(2- hydroxye...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details US Patent