BDBM785345 US12466840, Example Ex-2
SMILES CCc1c(F)cc2[nH]ncc2c1-c1nc2c3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c1F)N1CCCOC[C@H]1CO2
InChI Key
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 785345
Affinity DataIC50: 0.650nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.690nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.690nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.690nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.10nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.20nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.30nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.20nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.74E+3nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.02E+3nMAssay Description:To assemble the preformed TR-FRET complexes, each biotinylated RAS protein is diluted to 2 μM in an EDTA Buffer (20 mM HEPES pH 7.5, 50 mM sodium chl...More data for this Ligand-Target Pair
Ligand Info