BDBM785367 (R)-4-((3- ((dimethylamino) methyl)-4- (tetrahydrofuran- 3-yl)phenyl) amino)-7-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-1,2- dihydro-3H- pyrrolo[3,4- c]pyridin-3-one::US12466841, Compound I-19

SMILES CN(C)Cc1cc(Nc2ncc(-c3cnc4cc(F)ccn34)c3c2C(=O)NC3)ccc1[C@H]1CCOC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785367   

LigandChemical structure of BindingDB Monomer ID 785367BDBM785367((R)-4-((3- ((dimethylamino) methyl)-4- (tetrahydro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details