BDBM785451 US20250345339, Compound 14

SMILES Cc1cc(Nc2ncnn3ccc(-c4cnn(CCCC(=O)/C=C/CN(C)C)c4)c23)ccc1Oc1ccn2ncnc2c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 785451   

LigandChemical structure of BindingDB Monomer ID 785451BDBM785451(US20250345339, Compound 14)
Affinity DataIC50: 200nMAssay Description:The purpose of the wtERBB2, ERBB2-A775_G776insYVMA (ERBB2YVMA), wtEGFR biochemical assay was to evaluate the inhibition (% inhibition and IC50 values...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 785451BDBM785451(US20250345339, Compound 14)
Affinity DataIC50: 350nMAssay Description:The purpose of the wtERBB2, ERBB2-A775_G776insYVMA (ERBB2YVMA), wtEGFR biochemical assay was to evaluate the inhibition (% inhibition and IC50 values...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 785451BDBM785451(US20250345339, Compound 14)
Affinity DataIC50: 3.25E+3nMAssay Description:The purpose of the wtERBB2, ERBB2-A775_G776insYVMA (ERBB2YVMA), wtEGFR biochemical assay was to evaluate the inhibition (% inhibition and IC50 values...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details