BDBM785453 US20250345339, Compound Zongertinib

SMILES C=CC(=O)NC1CCN(c2ncc3ncnc(Nc4ccc(Oc5ccc6c(c5)ncn6C)c(C)c4)c3n2)CC1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 785453   

LigandChemical structure of BindingDB Monomer ID 785453BDBM785453(US20250345339, Compound Zongertinib)
Affinity DataKi:  94nMAssay Description:The purpose of the wtERBB2, ERBB2-A775_G776insYVMA (ERBB2YVMA), wtEGFR biochemical assay was to evaluate the inhibition (% inhibition and IC50 values...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 785453BDBM785453(US20250345339, Compound Zongertinib)
Affinity DataKi:  460nMAssay Description:The purpose of the wtERBB2, ERBB2-A775_G776insYVMA (ERBB2YVMA), wtEGFR biochemical assay was to evaluate the inhibition (% inhibition and IC50 values...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details