BDBM787201 N-(1-amino-3-phenylpropan-2-yl)-3-(1H-pyrazol-4-yl)-1H-indole-7-carboxamide::US20250346616, Example 147

SMILES NCC(Cc1ccccc1)NC(=O)c1cccc2c(-c3cn[nH]c3)c[nH]c12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 787201   

LigandChemical structure of BindingDB Monomer ID 787201BDBM787201(N-(1-amino-3-phenylpropan-2-yl)-3-(1H-pyrazol-4-yl...)
Affinity DataIC50: 0.400nMAssay Description:Recombinant ROCK1 and ROCK2 was purchased from Thermo Fisher with catalogue numbers PV3691 and PR71168. The inhibition potency of compounds against t...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/5/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787201BDBM787201(N-(1-amino-3-phenylpropan-2-yl)-3-(1H-pyrazol-4-yl...)
Affinity DataIC50: 0.880nMAssay Description:Recombinant ROCK1 and ROCK2 was purchased from Thermo Fisher with catalogue numbers PV3691 and PR71168. The inhibition potency of compounds against t...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/5/2026
Entry Details