BDBM787227 US12473262, Compound 849

SMILES COC(=O)c1ccc2nc(-c3cccc4ccccc34)n(C(=O)c3ccc(F)c(F)c3)c2c1

InChI Key InChIKey=IHGWVRBALCDHKA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 787227   

TargetCytochrome P450 2C19(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 4.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 7.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 1.51E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 1.93E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2B6(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 4.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787227BDBM787227(US12473262, Compound 849)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent