BDBM787809 (R)-2-((5-(2-(6-amino-2-methylhexan-3-yl)-2,6-diazaspiro[3.4]octan-6-yl)-3-chloro-1,2,4-triazin-6-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide::US12473295, Compound 406

SMILES CCN(C(=O)c1cc(F)ccc1OC1N=NC(Cl)=NC1N1CCC2(C1)CN([C@H](CCCN)C(C)C)C2)C(C)C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 787809   

TargetMenin(Human)TBA
LigandChemical structure of BindingDB Monomer ID 787809BDBM787809((R)-2-((5-(2-(6-amino-2-methylhexan-3-yl)-2,6-diaz...)
Affinity DataIC50: 33nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200× test compound in DMSO and 4 μL 2× terbium chelate-labeled menin (vide infra for...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787809BDBM787809((R)-2-((5-(2-(6-amino-2-methylhexan-3-yl)-2,6-diaz...)
Affinity DataIC50: 130nMAssay Description:To an untreated, white 384-well microtiter plate was added 40 nL 200× test compound in DMSO and 4 μL 2× terbium chelate-labeled menin (vide infra for...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details