BDBM787902 2-amino-N- cyclopropyl-5- (4-(2-(3,5- difluorophenyl)- 2- hydroxyacetamido)- 3-fluoro-2- methylphenyl) nicotinamide::2-amino-N-cyclopropyl-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-3-fluoro-2-methylphenyl)nicotinamide::US12473296, Example 120

SMILES Cc1c(-c2cnc(N)c(C(=O)NC3CC3)c2)ccc(NC(=O)C(O)c2cc(F)cc(F)c2)c1F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 787902   

LigandChemical structure of BindingDB Monomer ID 787902BDBM787902(2-amino-N- cyclopropyl-5- (4-(2-(3,5- difluorophen...)
Affinity DataIC50: 13nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details