BDBM788151 US12473303, Compound H-APPAMP-008

SMILES Cc1ccc2nc(CNc3cc(NC[C@H]4CCNC[C@@H]4O)nc4c(C(C)C)cnn34)cn2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 788151   

LigandChemical structure of BindingDB Monomer ID 788151BDBM788151(US12473303, Compound H-APPAMP-008)
Affinity DataIC50: 40nMAssay Description:(33PanQinase® Activity Assay) was used for measuring the kinase activity of the two protein kinases (CDK12/CDK7). All kinase assays were performed in...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 788151BDBM788151(US12473303, Compound H-APPAMP-008)
Affinity DataIC50: 117nMAssay Description:(33PanQinase® Activity Assay) was used for measuring the kinase activity of the two protein kinases (CDK12/CDK7). All kinase assays were performed in...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details