BDBM789169 UAMC-000-5379::US20250353833, Inhibitor MFE-2022-212

SMILES O=C(CNC12CC3CC(C1)CC(Nc1ccc(-c4ccccc4)nc1)(C3)C2)N1Cc2ccc(F)cc2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 789169   

TargetDipeptidyl peptidase 9(Human)TBA
LigandChemical structure of BindingDB Monomer ID 789169BDBM789169(UAMC-000-5379 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 0.00600nMAssay Description:Table 3 and 4: IC50 measurements. Enzyme activities were determined kinetically in 96-well half area plates (Greiner Bio-One) in a final volume of 10...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/10/2026
Entry Details

TargetDipeptidyl peptidase 8(Human)TBA
LigandChemical structure of BindingDB Monomer ID 789169BDBM789169(UAMC-000-5379 | US20250353833, Inhibitor MFE-2022-...)
Affinity DataIC50: 0.00900nMAssay Description:Table 3 and 4: IC50 measurements. Enzyme activities were determined kinetically in 96-well half area plates (Greiner Bio-One) in a final volume of 10...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/10/2026
Entry Details