BDBM789249 (R)-6-((1-((3-Amino-4-hydroxy-2-methylbutan-2-yl)sulfonyl)cyclopropyl)methyl)-N-(4-chlorobenzyl)-1-methyl-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide hydrochloride::US20250353820, Example 214

SMILES Cn1nc(C(=O)NCc2ccc(Cl)cc2)c2c1C(=O)N(CC1(S(=O)(=O)C(C)(C)[C@H](N)CO)CC1)CC2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 789249   

LigandChemical structure of BindingDB Monomer ID 789249BDBM789249((R)-6-((1-((3-Amino-4-hydroxy-2-methylbutan-2-yl)s...)
Affinity DataIC50: 3nMAssay Description:DNA polymerase activity was measured using a molecular beacon-based assay, as described in Ma et. al. 100 pM CMV polymerase or 625 pM HSV polymerase ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/10/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 789249BDBM789249((R)-6-((1-((3-Amino-4-hydroxy-2-methylbutan-2-yl)s...)
Affinity DataIC50: 32nMAssay Description:DNA polymerase activity was measured using a molecular beacon-based assay, as described in Ma et. al. 100 pM CMV polymerase or 625 pM HSV polymerase ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/10/2026
Entry Details