BDBM789782 2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethyl)-2,5-dimethylpiperazin-1-yl)-4-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)acetonitrile::US20250353858, Compound A10a

SMILES C[C@@H]1CN(c2cc(=O)n(C)c3cc(CC#N)nn23)[C@@H](C)CN1[C@@H](C)c1ccc2c(c1)OC(C)(C)CO2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 789782   

LigandChemical structure of BindingDB Monomer ID 789782BDBM789782(2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrobenzo[...)
Affinity DataIC50: 3nMAssay Description:Enzymatic reactions of DGKζ, DGKα and DGKδ were performed using ADP-Glo assay with lipid micelle substrate. Full length DGKζ in-house protein M1-V929...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 789782BDBM789782(2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrobenzo[...)
Affinity DataIC50: 2.89E+4nMAssay Description:Enzymatic reactions of DGKζ, DGKα and DGKδ were performed using ADP-Glo assay with lipid micelle substrate. Full length DGKζ in-house protein M1-V929...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details